Thursday, August 03, 2006

Curry & Onion for colorectal Cancer

Curry May Include Colorectal Cancer Preventive - CME Teaching Brief® - MedPage Today: "BALTIMORE, Aug. 2 -- Chemicals in curry and onions may put the heat on colorectal cancer, helping to reduce both the size and number of adenomas in patients genetically prone to them.
In a small pilot study, pills containing curcumin, a substance found in turmeric (a key ingredient of curry), and quercetin, an anti-oxidant derived from onions, kept the adenomas at bay, according to Francis Giardiello, M.D., of Johns Hopkins here.
In what Dr. Giardiello, described as a proof of principle, he and colleagues treated five patients with familial adenomatous polyposis (FAP) for six months with curcumin and quercetin, they reported in the August issue of the journal Clinical Gastroenterology and Hepatology. Patients with familial adenomatous polyposis develop hundreds of adenomas and eventually colon cancer.
The study found:
The number of adenomatous polyps decreased from baseline by 60.4%, on average.
The size of the polyps fell by 50.9%, on average.
Both changes were statistically significant at P<0.05.
Adverse effects were minimal and there were no laboratory abnormalities. "

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